Program Overview

Dr. Leong’s research area is in primary care with a special focus on mental health and pharmacy practice. Her program aims to optimize treatment strategies and to improve the quality of care for patients taking medications. Pharmacoepidemiology, qualitative research, and survey studies are primary methods used in this program.

Research Area:

Medication Use Experience and Optimization
What is the trend in prescription drug use in the Manitoba population and how has this impacted the health of Manitobans? Our lab aims to determine the extent of medication use and to identify those who may be at risk for unintended adverse outcomes as a result of drug therapy in the general population and in specific populations such as older adults, pregnant women, breastfeeding women, and children. We also aim to investigate the experiences of medication use through qualitative methods and determine ways in which medication therapy can be optimized in specific populations. Medications of interest include cannabinoids, antidepressants, opioids, stimulants, antiepileptics, lithium, antipsychotics, benzodiazepines and z-drug hypnotics.

Pharmacy Practice
Pharmacists play an important role in optimizing medication therapy. Our pharmacy practice research program includes: (1) Understanding how the performance of physical examination by a pharmacist for the purpose of drug therapy monitoring will impact patient care from the perspectives of the public, pharmacists, and other healthcare providers, and (2) Understanding the facilitators and barriers to intervening on patients who are at risk of medication misuse, diversion, and suicide in community pharmacy practice.  We also aim to explore communication gaps between community pharmacies and prescribers/service providers as it relates to providing care for patients with substance use disorder.

Publications and Presentations

Select Publications:
1. Leong C, Sareen J, Leslie, William, Enns M, Bolton J, Alessi-Severini S, Katz L, Logsetty S, Snider C, Berry J, Prior H, Chateau D. Validity of the Days Supply Field in Pharmacy Administrative Claims Data for the Identification of Blister Packaging of Medications. Pharmacoepidemiology Drug Safety & Efficacy August 2017;26(12):1540-5. Doi: 10.1002/pds.4288. [Epub aheqad of print].
2. Leong C, Raymond C, Chateau D, Dahl M, Falk J, Bugden S, Katz A. Psychotropic drug use before, during, and after pregnancy: A population-based cohort study (2001-2013). Published in The Canadian Journal of Psychiatry 2017;62(8):543-550.
3. Leong C, Alessi-Severini S, Enns MW, Nie Y, Sareen J, Bolton J, Prior HJ, Chateau D. Cerebrovascular, Cardiovascular, and Mortality Events in New Users of SSRIs and SNRIs: a propensity score-matched population-based study. J Clin Psychopharmacol 2017; 37(3):332-340.
4. Falk J, Dahl M, Raymond CB, Chateau D, Katz A, Leong C, Bugden S. Opioid use during pregnancy: A population-based cohort study. CMAJ Open 2017;5(2):E517-523.
5. Leong C. A Community Outreach Blood Pressure Clinic: Experiential practice site for pharmacy and dental hygiene students trained in physical assessment. Pharmacy Education 2016;16(1):182-88.
6. Sharif-Chan B, Tankala D, Leong, C, Austin Z, Battistella M. An Observational Case Study of Near-peer Teaching in Medical and Pharmacy Experiential Training. American Journal of Pharmaceutical Education 2016;80(70):Article 114.
7. Leong C, Alessi-Severini S, Sareen J, Enns MW, Bolton J. Community pharmacy practice perspectives on dispensing medications with the potential for misuse, diversion, and intentional overdose: Results of a province-wide survey of community pharmacists in Canada. Substance Use and Misuse 2016; 51(13):1724-30.
8. Leong C, Enns MW, Sareen J, Alessi-Severini S, Bolton J, Prior H, Chateau D. New antidepressant use in older adults: A Canadian population-based study (1997-2013). Aging and Mental Health 2017;21(7):720-729.
9. Leong C, Mamdani MM, Gomes TG, Juurlink DN, Macdonald EM, Yogendran M. Antiepileptic drug use for epilepsy and non-epilepsy disorders: A population-based study (1998-2013). Neurology 2016; 86(10):939-46.
10. Leong C, Lake J. Treating recurrent postmenopausal vasomotor symptoms in a patient with a positive family history for breast cancer: A case report. The Consultant Pharmacist 2015;30(1):38-44.
11. Leong C, Louizos C, Currie C, Glassford L, Davies N, Brothwell D, Renaud R. Student perspectives of an online module for teaching physical assessment skills for Dentistry, Dental Hygiene, and Pharmacy students. J of Interprof Care 2015;29(4):383-5.
12. Leong C, Louizos C, Frankel G, Ng S, Iacovides H, Falk J, Dunford D, Brink K, Kleiman N, Davis C, Renaud R. Implementation and Evaluation of a Physical Assessment Skills Module on Vital Signs for Pharmacy Students. American Journal for Pharmaceutical Education 2014;78(7):137.
13. Leong C. Antidepressants for Depression in Patients with Dementia: A Review of the Literature. The Consultant Pharmacist 2014;29(4):254-263.
14. Leong C, Zelenitsky S. Treatment Strategies for Recurrent Clostridium difficile Infection. The Canadian Journal of Hospital Pharmacy 2013;66(6):361-8.

Research Oral Presentations:
1. Leong C and Raymond C. Outpatient oral cancer medications in Manitoba. Evidence to Action: MCHP’s Annual Knowledge Exchange Workshop. November 24, 2016. Winnipeg, MB, Canada.
2. Leong C. The Initiation of a Blood Pressure Clinic for Enhancing the Educational Experiences of Pharmacy Students for Teaching Skills in Physical Assessment.  NABP/AACP 78th Annual Meeting. August 8, 2015. Fargo, ND, United States.